WunderFolk takes place in Los Angeles, in an alternate version of earth. Years ago, eighty percent of the human population was infected with the aids virus. Facing extinction, researchers finally discovered the cure to the virus was tucked away in animal dna. Since each person is genetically different, different people required the dna of different animals. Although the cure had no apparent side effect, the genes of some children born to those that had received the cure were altered. They were born with the ability to transform into human/animal hybrids. The hybrid type is dependent on what animal dna was used to synthesize the cure.
The story revolves around the main character, Mara Agosti, who is a Bengal tiger hybrid. She was a homicide detective who was framed for various murders. Deemed a serial killer, she is now on the run from the authorities. Although wanted, she still tries to help those in need if she's able.