Red Ghost + Thanos = double death for the FF! Susan Storm — the Invisible Woman — is headed toward a science conference in Siberia when her airplane is mysteriously shot out of the sky! With her survival in doubt, Reed Richards must abandon his completion of the equally enigmatic Cosmic Cube at its most crucial time to confront none other than the Ultimate Crimson Dynamo AND the Ultimate Red Ghost! Who shot down Sue – and can she survive the horrors hiding in the snow? Plus: Ultimate Thanos returns! What has placed the Baxter Building — and a huge chunk of New York City — under siege? Aliens are among us, hunting the greatest force in existence: the Cosmic Cube! And in the race to command this deadliest of weapons, treachery and overkill are the order of the day...even from former friends!