A spectacular spider-powered hero for a new generation! On the most tragic day of her life, Earth-65’s Gwen Stacy was convinced the Lizard died in her arms along with Peter Parker. Now a new reptilian rampage has left her in doubt — not only about Peter’s life, but also about his death! And Gwen’s troubles pile up as the Osborns of her world make their debut, and she finds herself on S.H.I.E.L.D.’s most wanted list. Perhaps another Spider-Woman, Jessica Drew, could share some lessons about power and responsibility! Get to know Gwen, her policeman father, George Stacy, and her BFFs and bandmates — the incomparable Mary Janes! Plus: more Earth-65 twists on familiar faces including Frank Castle, Matt Murdock and Captain America!