The Mr. Johnson comic is based on Amos Johnson, a 127-year-old superhuman who also happens to be a former slave, third-generation herbalist, and Decorated World War I Veteran. After sixty-six years of hiding and escaping genetic testing from Pharma-Life and the United States Government, Amos resurfaces and is dubbed "the most dangerous man alive" after an altercation between him and the police goes viral. It is now 2021, and Amos is on the run combating his former handlers' efforts to destroy him and the world.