Set in Victorian London, as four werewolves escape from London on a ship bound for the States.
In the Wild West a wagon train is encamped for the night but is soon attacked by werewolves, two survivors escape to hold up in a fort run by union soldiers guarding confederates soldiers from the civil war. Also hiding in the fort are six train robbers. However, once four bounty hunters show up in the fort mayhem begins as it is a full moon.
The union captain for the fort and his soldiers join forces with the confederates as the train robbers look for SILVER anywhere to repel the werewolves. The two wagon train survivors fight for their very lives along with other people in the fort.