The story starts with a bang as the Fantastic Four chase down the Sandman to stop a bank robbery! Afterwards, Reed, Sue, Ben, and Johnny return to the Baxter Building and agree to take a vacation to Colorado with Agatha Harkness. A vacation to the Rocky Mountains sounds great, but perhaps somewhere besides New Salem! Unbeknownst to the fabulous foursome, the Salem Seven are lying in wait to ambush them! And then steal the FF's powers to bring Nicholas Scratch back to Earth's realm! Back in New York City, the cataclysmic confrontation takes place: Agatha Harkness and young Franklin vs. Nicholas Scratch and the Salem Seven! Cameo appearances by Captain America, Captain Marvel, Falcon, Iron Man, Ms. Marvel, Nighthawk, Vision, Wonder Man, and Peter Parker.