Wakanda has been conquered, its Vibranium reserves plundered. Storm faces execution in the next 48 hours. And Dr. Doom stands triumphant. It will take the combined forces of the X-Men, the Fantastic Four and the two Black Panthers to stand against him. A war has begun that will pit the world's most relentless super villain against a collection of the world's most powerful super heroes--one that will span the globe, offering twists and turns and surprise players (hello Deadpool!) that neither side will see coming.